1) Eu.Gene Analyzer Download: a) Download and save EuGene.zip file in a temporary folder (i.e. C:\temp in Windows OS) b) Unzip (extract) EuGene.zip file in your preferred destination folder (i.e. C:\EuGene11) c) Double (left) click EuGene.cmd file (or EuGene.sh in Unix/Linux) to launch the program d) At the first startup, EuGene will ask for a specific root folder where data/pathway structure can be created: it is possible to select the same directory where the program has ben saved (i.e. C:\EuGene11) » Download EuGene (DC-Thera version) – ZIP-File, 7.6 MB IMPORTANT NOTE: Eu.Gene Analyzer standard version support Saccharomyces cervisae genome only. Genome Libraries for Homo sapiens, Rattus norvegicus and Mus musculus can be downloaded and saved into the software dedicate folder named “lib”. 2) Genome Libraries Download: a) Choose an Organism and download the Genome Library "*.lib" file from the list below. b) Save "*.zip" file in "/lib" folder (i.e. C:\EuGene11\lib) that has been created after the first Eugene Analyzer starting-up. Extract file named "*.lib". » Download - Homo Sapiens Genome [NCBI36] (DC-Thera version) – LIB-File, 7.1 MB » Download - Mus Musculus Genome [MCBI 36] – LIB-File, 5.3 MB » Download - Rattus Norvegicus Genome [RGSC 34] – LIB-File, 2.5 MB » Download - Saccharomyces Cerevisiae Genome [SGD 1] – LIB-File, 126.9 KB 3) User Manual Download: EuGene_User_Manual.pdf 4) Supplementary Information Download: suppMat.zip TABLE_1.doc TABLE_2.doc Appendix-TABLE-1.doc Appendix-TABLE-2.doc