1) Eu.Gene Analyzer Download: a) Download and save EuGene.zip file in a temporary folder (i.e. C:\temp in Windows OS) b) Unzip (extract) EuGene.zip file in your preferred destination folder (i.e. C:\EuGene14) c) Double (left) click EuGene.cmd file (or EuGene.sh in Unix/Linux) to launch the program d) At the first startup, EuGene will ask for a specific root folder where data/pathway structure can be created: it is possible to select the same directory where the program has ben saved (i.e. C:\EuGene14) » Download EuGene (standard version) v1.4 – ZIP-File, 40.4 MB Genome Libraries for Homo sapiens, Rattus norvegicus and Mus musculus can be downloaded and saved into the software dedicate folder named “lib”. 2) Genome Libraries Download: a) Choose an Organism and download the Genome Library "*.lib" file from the list below. b) Save "*.zip" file in "/lib" folder (i.e. C:\EuGene11\lib) that has been created after the first Eugene Analyzer starting-up. Extract file named "*.lib". » Download - Homo Sapiens Genome [NCBI36] (standard) – LIB-File, 6.42 MB Updated to Ensembl Version 49 » Download - Mus Musculus Genome [MCBI 36] – LIB-File, 5.3 MB » Download - Rattus Norvegicus Genome [RGSC 34] – LIB-File, 2.5 MB » Download - Saccharomyces Cerevisiae Genome [SGD 1] – LIB-File, 95.8 KB Updated to Ensembl Version 49 3) User Manual Download: EuGene_User_Manual.pdf 4) Supplementary Information Download: suppMat.zip TABLE_1.doc TABLE_2.doc Appendix-TABLE-1.doc Appendix-TABLE-2.doc